synergyfinder

This package is for version 3.9 of Bioconductor; for the stable, up-to-date release version, see synergyfinder.

Calculate and Visualize Synergy Scores for Drug Combinations


Bioconductor version: 3.9

Efficient implementations for all the popular synergy scoring models for drug combinations, including HSA, Loewe, Bliss and ZIP and visualization of the synergy scores as either a two-dimensional or a three-dimensional interaction surface over the dose matrix.

Author: Liye He <liye.he at helsinki.fi>, Jing Tang <jing.tang at helsinki.fi>, Shuyu Zheng <shuyu.zheng at helsinki.fi>

Maintainer: Shuyu Zheng <shuyu.zheng at helsinki.fi>

Citation (from within R, enter citation("synergyfinder")):

Installation

To install this package, start R (version "3.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("synergyfinder")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("synergyfinder")
synergyfinder PDF R Script
Reference Manual PDF
NEWS Text

Details

biocViews Software, StatisticalMethod
Version 1.10.7
In Bioconductor since BioC 3.4 (R-3.3) (7.5 years)
License Mozilla Public License 2.0
Depends R (>= 3.6.0)
Imports drc (>= 2.5-12), reshape2 (>= 1.4.1), SpatialExtremes (>= 2.0-2), ggplot2 (>= 2.1.0), grid (>= 3.2.4), lattice (>= 0.20-33), nleqslv (>= 3.0), stats (>= 3.3.0), graphics (>= 3.3.0), grDevices (>= 3.3.0)
System Requirements
URL
See More
Suggests knitr, rmarkdown
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package synergyfinder_1.10.7.tar.gz
Windows Binary synergyfinder_1.10.7.zip (32- & 64-bit)
Mac OS X 10.11 (El Capitan) synergyfinder_1.10.7.tgz
Source Repository git clone https://git.bioconductor.org/packages/synergyfinder
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/synergyfinder
Bioc Package Browser https://code.bioconductor.org/browse/synergyfinder/
Package Short Url https://bioconductor.org/packages/synergyfinder/
Package Downloads Report Download Stats
Old Source Packages for BioC 3.9 Source Archive