qpgraph

Reverse engineering of molecular regulatory networks with qp-graphs

Bioconductor version: 2.6

q-order partial correlation graphs, or qp-graphs for short, are undirected Gaussian graphical Markov models built from q-order partial correlations. They are useful for learning undirected graphical Gaussian Markov models from data sets where the number of random variables p exceeds the available sample size n as, for instance, in the case of microarray data where they can be employed to reverse engineer a molecular regulatory network.

Author: R. Castelo and A. Roverato

Maintainer: Robert Castelo <robert.castelo at upf.edu>

To install this package, start R and enter:

    source("http://bioconductor.org/biocLite.R")
    biocLite("qpgraph")

To cite this package in a publication, start R and enter:

    citation("qpgraph")

Documentation

PDF qpPCCdistbyTF.pdf
PDF qpPreRecComparison.pdf
PDF qpPreRecComparisonFullRecall.pdf
PDF qpTRnet50pctpre.pdf
PDF R Script Reverse-engineer transcriptional regulatory networks using qpgraph
PDF   Reference Manual

Details

biocViews Microarray, GeneExpression, Transcription, Pathways, Bioinformatics, GraphsAndNetworks
Depends methods, Biobase(>= 2.5.5), AnnotationDbi
Imports methods, Biobase(>= 2.5.5), AnnotationDbi
Suggests mvtnorm, graph, Rgraphviz, annotate, genefilter, Category(>= 2.9.7), org.EcK12.eg.db(>= 2.2.6), GOstats
System Requirements
License GPL (>= 2)
URL http://functionalgenomics.upf.edu/qpgraph
Depends On Me
Imports Me
Suggests Me
Version 1.4.1
Since Bioconductor 2.4 (R-2.9)

Package Downloads

Package Source qpgraph_1.4.1.tar.gz
Windows Binary qpgraph_1.4.1.zip (32- & 64-bit)
MacOS 10.5 (Leopard) binary qpgraph_1.4.1.tgz
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