Package: pfamAnalyzeR
Type: Package
Title: Identification of domain isotypes in pfam data
Version: 1.10.0
Authors@R: person(given="Kristoffer",family="Vitting-Seerup", role=c("cre","aut"),email="k.vitting.seerup@gmail.com",comment = c(ORCID = "0000-0002-6450-0608"))
Description: Protein domains is one of the most import annoation of
        proteins we have with the Pfam database/tool being (by far) the
        most used tool. This R package enables the user to read the
        pfam prediction from both webserver and stand-alone runs into
        R. We have recently shown most human protein domains exist as
        multiple distinct variants termed domain isotypes. Different
        domain isotypes are used in a cell, tissue, and
        disease-specific manner. Accordingly, we find that domain
        isotypes, compared to each other, modulate, or abolish the
        functionality of a protein domain. This R package enables the
        identification and classification of such domain isotypes from
        Pfam data.
License: MIT + file LICENSE
Depends: R (>= 4.3.0), readr, stringr, dplyr
Imports: utils, tibble, magrittr
Encoding: UTF-8
RoxygenNote: 7.2.1
Suggests: BiocStyle, knitr, rmarkdown
VignetteBuilder: knitr
biocViews: AlternativeSplicing, TranscriptomeVariant,
        BiomedicalInformatics, FunctionalGenomics, SystemsBiology,
        Annotation, FunctionalPrediction, GenePrediction, DataImport
BugReports: https://github.com/kvittingseerup/pfamAnalyzeR/issues
Config/pak/sysreqs: libicu-dev libx11-dev
Repository: https://bioc-release.r-universe.dev
Date/Publication: 2025-10-29 15:23:16 UTC
RemoteUrl: https://github.com/bioc/pfamAnalyzeR
RemoteRef: RELEASE_3_22
RemoteSha: f357ad4c46a7f4a757b96729b4b35fea390dafc8
NeedsCompilation: no
Packaged: 2025-11-17 07:36:31 UTC; root
Author: Kristoffer Vitting-Seerup [cre, aut] (ORCID:
    <https://orcid.org/0000-0002-6450-0608>)
Maintainer: Kristoffer Vitting-Seerup <k.vitting.seerup@gmail.com>
Built: R 4.5.2; ; 2025-11-17 07:37:41 UTC; windows
