Bioconductor release scheduled for October 29

STADyUM

This is the development version of STADyUM; to use it, please install the devel version of Bioconductor.

Statistical Transcriptome Analysis under a Dynamic Unified Model


Bioconductor version: Development (3.22)

STADyUM is a package with functionality for analyzing nascent RNA read counts to infer transcription rates. This includes utilities for processing experimental nascent RNA read counts as well as for simulating PRO-seq data. Rates such as initiation, pause release and landing pad occupancy are estimated from either synthetic or experimental data. There are also options for varying pause sites and including steric hindrance of initiation in the model.

Author: Yixin Zhao [aut] ORCID iD ORCID: 0000-0002-7856-2818 , Lingjie Liu [aut] ORCID iD ORCID: 0000-0002-5765-1213 , Rebecca Hassett [aut, cre] ORCID iD ORCID: 0000-0001-5133-9387

Maintainer: Rebecca Hassett <hassett at cshl.edu>

Citation (from within R, enter citation("STADyUM")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("STADyUM")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("STADyUM")
STADyUM: Simulating and Analyzing Transcription Dynamics HTML R Script
Reference Manual PDF

Details

biocViews Sequencing, Software, StatisticalMethod, Transcription, Transcriptomics
Version 0.99.4
In Bioconductor since BioC 3.22 (R-4.5)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports GenomicRanges, IRanges, S4Vectors, methods, tibble, dplyr, ggplot2, progress, plyranges, GenomeInfoDb, Rcpp, data.table, purrr, rtracklayer, tidyr, rlang, MASS
System Requirements
URL https://github.com/rhassett-cshl/STADyUM
Bug Reports https://github.com/rhassett-cshl/STADyUM
See More
Suggests testthat (>= 3.0.0), knitr, rmarkdown, devtools
Linking To Rcpp
Enhances
Depends On Me
Imports Me
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Links To Me
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package STADyUM_0.99.4.tar.gz
Windows Binary (x86_64)
macOS Binary (x86_64) STADyUM_0.99.4.tgz
macOS Binary (arm64) STADyUM_0.99.4.tgz
Source Repository git clone https://git.bioconductor.org/packages/STADyUM
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/STADyUM
Bioc Package Browser https://code.bioconductor.org/browse/STADyUM/
Package Short Url https://bioconductor.org/packages/STADyUM/
Package Downloads Report Download Stats