Bioconductor release scheduled for October 29

SmartPhos

This is the development version of SmartPhos; to use it, please install the devel version of Bioconductor.

A phosphoproteomics data analysis package with an interactive ShinyApp


Bioconductor version: Development (3.22)

To facilitate and streamline phosphoproteomics data analysis, we developed SmartPhos, an R package for the pre-processing, quality control, and exploratory analysis of phosphoproteomics data generated by MaxQuant and Spectronaut. The package can be used either through the R command line or through an interactive ShinyApp called SmartPhos Explorer. The package contains methods such as normalization and normalization correction, transformation, imputation, batch effect correction, PCA, heatmap, differential expression, time-series clustering, gene set enrichment analysis, and kinase activity inference.

Author: Shubham Agrawal [aut, cre] ORCID iD ORCID: 0009-0005-2630-9342 , Junyan Lu [aut] ORCID iD ORCID: 0000-0002-9211-0746

Maintainer: Shubham Agrawal <shubhamagrawal2706 at gmail.com>

Citation (from within R, enter citation("SmartPhos")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("SmartPhos")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("SmartPhos")
Introduction to Shiny App HTML R Script
Introduction to SmartPhos HTML R Script
Reference Manual PDF

Details

biocViews BatchEffect, Clustering, DifferentialExpression, GUI, GeneExpression, GeneSetEnrichment, MassSpectrometry, Normalization, Preprocessing, Proteomics, QualityControl, ShinyApps, Software, Visualization
Version 0.99.30
In Bioconductor since BioC 3.22 (R-4.5)
License GPL-3
Depends R (>= 4.4.0)
Imports MultiAssayExperiment, SummarizedExperiment, data.table, shiny, shinythemes, shinyjs, shinyBS, shinyWidgets, parallel, DT, tools, stats, ggplot2, plotly, ggbeeswarm, pheatmap, grid, XML, MsCoreUtils, imputeLCMD, missForest, limma, proDA, decoupleR, piano, BiocParallel, doParallel, doRNG, e1071, magrittr, matrixStats, rlang, stringr, tibble, dplyr, tidyr, Biobase, vsn, factoextra, cowplot
System Requirements
URL https://lu-group-ukhd.github.io/SmartPhos/
Bug Reports https://github.com/Bioconductor/SmartPhos/issues
See More
Suggests knitr, BiocStyle, PhosR, testthat
Linking To
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package SmartPhos_0.99.30.tar.gz
Windows Binary (x86_64)
macOS Binary (x86_64) SmartPhos_0.99.30.tgz
macOS Binary (arm64) SmartPhos_0.99.30.tgz
Source Repository git clone https://git.bioconductor.org/packages/SmartPhos
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/SmartPhos
Bioc Package Browser https://code.bioconductor.org/browse/SmartPhos/
Package Short Url https://bioconductor.org/packages/SmartPhos/
Package Downloads Report Download Stats