## ----results='hide', message=FALSE-------------------------------------------- library(geneSLOPE) famFile <- system.file("extdata", "plinkPhenotypeExample.fam", package = "geneSLOPE") mapFile <- system.file("extdata", "plinkMapExample.map", package = "geneSLOPE") snpsFile <- system.file("extdata", "plinkDataExample.raw", package = "geneSLOPE") ## ----------------------------------------------------------------------------- phenotype <- read_phenotype(filename = famFile) ## ----warning=FALSE------------------------------------------------------------ screening.result <- screen_snps(snpsFile, mapFile, phenotype, pValMax = 0.05, chunkSize = 1e2, verbose=FALSE) ## ----------------------------------------------------------------------------- summary(screening.result) ## ----------------------------------------------------------------------------- clumping.result <- clump_snps(screening.result, rho = 0.3, verbose = FALSE) ## ----------------------------------------------------------------------------- summary(clumping.result) ## ----warning=FALSE, fig.height=7, fig.width=7--------------------------------- plot(clumping.result) ## ----warning=FALSE, fig.height=6, fig.width=6--------------------------------- plot(clumping.result, chromosomeNumber = 1) ## ----eval=FALSE--------------------------------------------------------------- # plot(clumping.result) # identify_clump(clumping.result) ## ----warning=FALSE, fig.height=6, fig.width=6--------------------------------- plot(clumping.result, clumpNumber = 1) ## ----------------------------------------------------------------------------- slope.result <- select_snps(clumping.result, fdr=0.1) ## ----warning = FALSE, fig.height=7, fig.width=7------------------------------- summary(slope.result) plot(slope.result) ## ----eval=FALSE--------------------------------------------------------------- # plot(slope.result) # identify_clump(slope.result) ## ----warning = FALSE, fig.height=7, fig.width=7------------------------------- plot(slope.result, clumpNumber = 1) ## ----------------------------------------------------------------------------- slope.result$selectedSnpsNumbers ## ----------------------------------------------------------------------------- slope.result$X_info[slope.result$selectedSnpsNumbers,] ## ----------------------------------------------------------------------------- summary(slope.result, clumpNumber = 1)