RepeatABEL: GWAS for Multiple Observations on Related Individuals

Performs genome-wide association studies (GWAS) on individuals that are both related and have repeated measurements. For each Single Nucleotide Polymorphism (SNP), it computes score statistic based p-values for a linear mixed model including random polygenic effects and a random effect for repeated measurements. The computed p-values can be visualized in a Manhattan plot. For more details see Ronnegard et al. (2016) <doi:10.1111/2041-210X.12535> and for more examples see <https://github.com/larsronn/RepeatABEL_Tutorials>.

Version: 2.0
Depends: hglm, methods
Published: 2026-01-06
DOI: 10.32614/CRAN.package.RepeatABEL
Author: Lars Ronnegard [aut, cre]
Maintainer: Lars Ronnegard <lars.ronnegard at slu.se>
License: GPL-2 | GPL-3 [expanded from: GPL]
NeedsCompilation: no
Citation: RepeatABEL citation info
Materials: NEWS
CRAN checks: RepeatABEL results

Documentation:

Reference manual: RepeatABEL.html , RepeatABEL.pdf

Downloads:

Package source: RepeatABEL_2.0.tar.gz
Windows binaries: r-devel: RepeatABEL_2.0.zip, r-release: RepeatABEL_2.0.zip, r-oldrel: RepeatABEL_2.0.zip
macOS binaries: r-release (arm64): RepeatABEL_2.0.tgz, r-oldrel (arm64): RepeatABEL_2.0.tgz, r-release (x86_64): RepeatABEL_2.0.tgz, r-oldrel (x86_64): RepeatABEL_2.0.tgz
Old sources: RepeatABEL archive

Linking:

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