Fit and compare nonlinear mixed-effects models in differential
equations with flexible dosing information commonly seen in pharmacokinetics
and pharmacodynamics (Almquist, Leander, and Jirstrand 2015
<doi:10.1007/s10928-015-9409-1>). Differential equation solving is
by compiled C code provided in the 'rxode2' package
(Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).
| Version: |
4.0.1 |
| Imports: |
cli (≥ 1.0.0), crayon (≥ 1.3.4), dplyr (≥ 0.7.4), purrr (≥
0.2.4), rstudioapi (≥ 0.7), nlmixr2est (≥ 2.2.2), nlmixr2extra (≥ 2.0.10), rxode2 (≥ 2.1.3), lotri (≥ 0.4.3), nlmixr2plot (≥ 2.0.8), tibble, magrittr |
| Suggests: |
rmarkdown, knitr, devtools, ggplot2, testthat, n1qn1, withr |
| Published: |
2025-08-29 |
| DOI: |
10.32614/CRAN.package.nlmixr2 |
| Author: |
Matthew Fidler 
[aut, cre],
Anne Keunecke [ctb],
Rik Schoemaker
[ctb],
Justin Wilkins
[ctb],
Wenping Wang [ctb],
Mirjam Trame [ctb],
John Harrold [ctb],
Bill Denney [ctb],
Theodoros Papathanasiou [ctb],
Richard Hooijmaijers [ctb],
Michael Wayne Kearney
[ctb] |
| Maintainer: |
Matthew Fidler <matthew.fidler at gmail.com> |
| BugReports: |
https://github.com/nlmixr2/nlmixr2/issues/ |
| License: |
GPL (≥ 3) |
| URL: |
https://nlmixr2.org/, https://github.com/nlmixr2/nlmixr2/ |
| NeedsCompilation: |
no |
| Citation: |
nlmixr2 citation info |
| Materials: |
README, NEWS |
| In views: |
DifferentialEquations, HighPerformanceComputing, MixedModels, Pharmacokinetics |
| CRAN checks: |
nlmixr2 results |